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According to Bryan Johnson, his health may have suffered more negative effects from using rapamycin than positive ones.
Patients undergoing transplantation usually take rapamycin to assist avoid organ rejection.
(Photo Credits: Instagram)
Anti-ageing influencer and IT entrepreneur Bryan Johnson has stopped taking a medication that has been helping him live longer. The 47-year-old millionaire shot to fame with his effort to turn back the clock on his biological age. Johnson had been taking 13 milligrams of the immunosuppressant rapamycin to live “forever” for the previous five years. However, he has now stopped the medication after discovering its negligible benefits were exceeded by its negative side effects.
Patients undergoing transplantation usually take rapamycin to assist avoid organ rejection. The drug might have caused more harm than good, according to Johnson, who implemented the “most aggressive rapamycin protocol of anyone in the industry.”
“On September 28, I decided to stop rapamycin, bringing an end to nearly 5 years of experimentation with this molecule for its longevity potential,” stated Johnson, who is featured in a new Netflix documentary about him, “Don’t Die: The Man Who Wants to Live Forever.”
“Despite the immense potential from pre-clinical trials, my team and I came to the conclusion that the benefits of lifelong dosing of Rapamycin do not justify the hefty side effects,” Johnson added.
According to the former Silicon Valley CEO, preclinical and clinical studies have shown that long-term rapamycin usage can cause insulin and glucose intolerance as well as affect lipid metabolism. As per The New York Post, Johnson admitted that he had stopped taking rapamycin after filming the documentary and that it might have had the opposite effect of what was intended.
In an attempt to halt, if not reverse, the ageing process, Johnson spends $2 million annually on medical tests and therapies in addition to a carefully planned diet, sleep schedule, and exercise routine.
Johnson reportedly has disclosed that he had a complete plasma exchange a few months ago, according to which pure albumin—a protein present in a person’s blood plasma—was used to replace the fluid in his body. The procedure was different from the time he exchanged blood with his adolescent son, whom he oddly referred to as “blood boy” in 2023, he emphasised.
Bryan Johnson is known for founding Braintree, a mobile and web payment solution for e-commerce companies, which was later acquired by PayPal. After selling off his company, Johnson is now dedicated to anti-ageing efforts. He is also the founder of Kernel, a neurotechnology firm that makes specially designed helmets to measure brain activities.
